THE ALKYLATION AND HALOGENATION OF SULFONES CATALYZED BY HYDROXIDE ION IN APROTIC SOLVENTSREGIS RR; DOWEYKO AM.1982; TETRAHEDRON LETT.; ISSN 0040-4039; GBR; DA. 1982; VOL. 23; NO 25; PP. 2539-2542; BIBL. 12 REF.Article

GLYOXALASE I ENZYME STUDIES. IV. GENERAL BASE CATALYZED ENEDIOL PROTON TRANSFER REARRANGEMENT OF METHYL- AND PHENYLGLYOXALGLUTATHIONYLHEMITHIOL ACETAL TO S-LACTOYL- AND S-MANDELOYLGLUTATHIONE FOLLOWED BY HYDROLYSIS. A MODEL FOR THE GLYOXALASE ENZYME SYSTEM.HALL SS; DOWEYKO AM; JORDAN F et al.1978; J. AMER. CHEM. SOC.; USA; DA. 1978; VOL. 100; NO 18; PP. 5934-5939; BIBL. 22 REF.Article

CLYOXALASE I ENZYME STUDIES. II. NUCLEAR MAGNETIC RESONANCE EVIDENCE FOR AN ENEDIOL-PROTON TRANSFER MECHANISM.HALL SS; DOWEYKO AM; JORDAN F et al.1976; J. AMER. CHEM. SOC.; U.S.A.; DA. 1976; VOL. 98; NO 23; PP. 7460-7461; BIBL. 17 REF.Article

A NOVEL CLASS OF FUNGICIDES: (2-PYRIDYLTHIO) METHYL BENZOATE N-OXIDESSTANTON DT; DAVIS RA; DOWEYKO AM et al.1983; JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY; ISSN 0021-8561; USA; DA. 1983; VOL. 31; NO 2; PP. 451-453; BIBL. 9 REF.Article

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS FOR 2-((PHENYLMETHYL) SULFONYL) PYRIDINE 1-OXIDE HERBICIDESDOWEYKO AM; BELL AR; MINATELLI JA et al.1983; JOURNAL OF MEDICINAL CHEMISTRY; ISSN 0022-2623; USA; DA. 1983; VOL. 26; NO 4; PP. 475-478; BIBL. 9 REF.Article

SYNTHESIS AND EVALUATION OF ALPHA -HYDROXYTHIOL ESTERS AS ANTITUMOR AGENTS AND GLYOXALASE I INHIBITORS.HALL SS; DOWEYKO LM; DOWEYKO AM et al.1977; J. MEDICIN. CHEM.; U.S.A.; DA. 1977; VOL. 20; NO 10; PP. 1239-1242; BIBL. 20 REF.Article

Three-dimensional pharmacophores from binding dataDOWEYKO, A. M.Journal of medicinal chemistry (Print). 1994, Vol 37, Num 12, pp 1769-1778, issn 0022-2623Article

The hypothetical active site lattice. An approach to modelling active sites from data on inhibitor moleculesDOWEYKO, A. M.Journal of medicinal chemistry (Print). 1988, Vol 31, Num 7, pp 1396-1406, issn 0022-2623Article

New tool for the study of structure-activity relationships in three dimensions: the hypothetical active-site latticeDOWEYKO, A. M.A.C.S. symposium series. 1989, Num 413, pp 82-104, issn 0097-6156, 23 p.Conference Paper

An application of 3D-QSAR to the analysis of the sequence specificity of DNA alkylation by uracil mustardDOWEYKO, A. M; MATTES, W. B.Biochemistry (Easton). 1992, Vol 31, Num 39, pp 9388-9392, issn 0006-2960Article

Antiulcer agents. 6. Analysis of the in vitro biochemical and in vivo gastric antisecretory activity of substituted imidazo[1,2-a]pyridines and related analogues using comparative molecular field analysis and hypothetical active site lattice methodologiesKAMINSKI, J. J; DOWEYKO, A. M.Journal of medicinal chemistry (Print). 1997, Vol 40, Num 4, pp 427-436, issn 0022-2623Article

Discovery of novel dihydro-9,10-ethano-anthracene carboxamides as glucocorticoid receptor modulatorsYANG, Bingwei V; VACCARO, Wayne; HABTE, Sium et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 8, pp 2139-2143, issn 0960-894X, 5 p.Article

Synthesis of H-3 labeled 5-fluoro-3-[3-[4-(5-methoxy-4-pyrimidinyl)-1-piperazinyl]propyl]-1H-indole, a serotonergic agent with potential antidepressant activityDISCHINO, D. D; COMBRINK, K. D; DOWEYKO, L et al.Journal of labelled compounds & radiopharmaceuticals. 1995, Vol 36, Num 8, pp 789-794, issn 0362-4803Article

A new class of high affinity thyromimetics containing a phenyl-naphthylene coreHANGELAND, Jon J; FRIENDS, Todd J; DOWEYKO, Arthur M et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 20, pp 4579-4584, issn 0960-894X, 6 p.Article

Estimation of hERG inhibition of drug candidates using multivariate property and pharmacophore SARJOHNSON, Stephen R; HONGWEN YUE; LEE CONDER, Mary et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 18, pp 6182-6192, issn 0968-0896, 11 p.Article

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56^lck inhibitorsDAS, Jagabandhu; MOQUIN, Robert V; SCHIEVEN, Gary L et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 15, pp 2587-2590, issn 0960-894X, 4 p.Article

Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitorsATWAL, Karnail S; O'NEIL, Steven V; AHMAD, Saleem et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 18, pp 4796-4799, issn 0960-894X, 4 p.Article

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Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor betaHANGELAND, Jon J; DOWEYKO, Arthur M; FÄRNEGARDH, Mathias et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 13, pp 3549-3553, issn 0960-894X, 5 p.Article

Molecular design, synthesis, and structure-activity relationships leading to the potent and selective p56^lck inhibitor BMS-243117DAS, Jagabandhu; LIN, James; PITT, Sidney et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 13, pp 2145-2149, issn 0960-894X, 5 p.Article

Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56^LckWITYAK, John; DAS, Jagabandhu; QIONG FANG et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 22, pp 4007-4010, issn 0960-894X, 4 p.Article

Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitorsSHUQUN LIN; WROBLESKI, Stephen T; KIEFER, Susan E et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 19, pp 5864-5868, issn 0960-894X, 5 p.Article

Synthesis and SAR of p38α MAP kinase inhibitors based on heterobicyclic scaffoldsMURALI DHAR, T. G; WROBLESKI, Stephen T; MATHUR, Arvind et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 18, pp 5019-5024, issn 0960-894X, 6 p.Article

Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitorsDAS, Jagabandhu; FURCH, Joseph A; HUNG, Chen-Yi et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 14, pp 3706-3712, issn 0960-894X, 7 p.Article

5-Amino-pyrazoles as potent and selective p38α inhibitorsDAS, Jagabandhu; MOQUIN, Robert V; NEWITT, John A et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 23, pp 6886-6889, issn 0960-894X, 4 p.Article